Isolation of beta-lactamase-producing Bacteroides strains associated with clinical failures with penicillin treatment of human orofacial infections |
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| Authors: | A Heimdahl L von Konow C E Nord |
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| Affiliation: | Departments of Oral Surgery and Oral Microbiology, Huddinge University Hospital, Karolinska Institute and National Bacteriological Laboratory, Stockholm, Sweden |
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| Abstract: | ![]()
Five patients with orofacial infection which failed to respond to penicillin therapy are described. In each instance, β-lactamase producing Bacteroides strains were found. All strains were resistant to penicillin but sensitive to clindamycin and tinidazole. In two cases, extended surgical treatment cured the patient, but in the other three cases additional clindamycin therapy was required. |
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