贲门周围血管离断术治疗门静脉高压症疗效的Meta分析

目的分析贲门周围血管离断术治疗门静脉高压症的效果及其主要术后并发症的发生率情况。方法检索Medline、Elsevier、PubMed、中国期刊全文数据库及万方数据库中关于贲门周围血管离断术治疗门静脉高压症的中英文文献，采用R．2．15软件进行Meta分析。结果共检索出中英文文献671篇，依据纳入标准和排除标准，最终入选23篇文献。Meta分析结果显示，贲门周围血管离断术治疗门静脉高压症的效果为：再出血率为2l％（95％CI：0．18～0．24），肝性脑病发生率为4％（95％CI：0．02～0．06），腹水发生率为29％（95％CI：0．14～0．47）；手术死亡率为3％（95％CI：0．02～0．04），死亡率为23％（95％CI：0．15～0．33）。结论贲门周围血管离断术仍具有一定的术后并发症发生率，其中临床最为常见且易导致死亡的是再出血，有必要对该术式做进一步的改进。

Meta-Analysis of Effect in Pericardial Devascularization for Patients with Portal Hypertension

Objective To analyze the effect and incidence rate of major postoperative complications ofpericardial devascularization in treatment of portal hypertension. Methods English and Chinese literatures about pericardial deva- scularization in treatment of portal hypertension were searched through Medline, Elsevier, PubMed, CNKI, and WanFang database, and meta analysis was taken in the process by using R-2.15 software. Results In total of 671 literatures were searched and 23 were selected finally according to inclusion criteria and exclusion criteria. The results of meta analysis showed that, the effect of pericardial devascularization in treatment of portal hypertension were as follows： the incidence rate ofrebleeding was 21% （95% CI： 0. 18-0.24）, the incidence rate of hepatic encephalopathy was 4% （95% CI： 0. 02- 0. 06）, the incidence rate ofascites was 29% （95% CI： 0. 14-0. 47）, mortality of operation was 3% （95% CI：0. 02-0. 04）, mortality was 23% （95% CI： 0. 15-0. 33）. Conclusions There is a certain incidence rate of complications ofpericardial devascularization, of which the most common complication is rebleeding. So, it is necessary to do further improvement and development of pericardial devascularization.