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高压氧联合依达拉奉治疗急性一氧化碳中毒迟发型脑部患者的临床价值分析
引用本文:许洁东. 高压氧联合依达拉奉治疗急性一氧化碳中毒迟发型脑部患者的临床价值分析[J]. 罕少疾病杂志, 2020, 27(4): 9-11. DOI: 10.3969/j.issn.1009-3257.2020.04.004
作者姓名:许洁东
作者单位:广东省广州市番禺区沙湾人民医院急诊科 广东广州 511400
摘    要:目的 探讨高压氧联合依达拉奉治疗急性一氧化碳中毒迟发性脑部患者的临床价值分析.方法 选取我院治疗104例脑出血患者作为研究对象,随机分为对照组与观察组各31例,对照组患者进行高压氧治疗,每天1次,持续十天为一疗程;观察组在对照组的治疗基础上联合依达拉奉30mg注入100ml0.9%氯化钠注射液中进行静脉滴注,每天2次,...

关 键 词:高压氧  依达拉奉  急性一氧化碳中毒  迟发性脑病

Clinical Value of Hyperbaric Oxygen Combined with Edaravone in the Treatment of Patients with Delayed Encephalopathy Caused by Acute Carbon Monoxide Poisoning
XU Jie-dong. Clinical Value of Hyperbaric Oxygen Combined with Edaravone in the Treatment of Patients with Delayed Encephalopathy Caused by Acute Carbon Monoxide Poisoning[J]. Journal of Rare and Uncommon Diseases, 2020, 27(4): 9-11. DOI: 10.3969/j.issn.1009-3257.2020.04.004
Authors:XU Jie-dong
Affiliation:(Department of Emergency,Shawan People's Hospital,Panyu District,Guangzhou 511400,Guangdong Province,China)
Abstract:Objective To investigate the clinical value of hyperbaric oxygen combined with edaravone in the treatment of patients with delayed encephalopathy caused by acute carbon monoxide poisoning.Method 104 patients with cerebral hemorrhage were selected as the study subjects in our hospital.They were randomly divided into control group and observation group,31 cases in each group.The patients in the control group were treated with hyperbaric oxygen once a day for 10 days.The patients in the observation group were supplemented with 30 mg edaravone injected into 100 ml 0.9%sodium chloride injection for intravenous infusion.2 times a day for 10 days as a course of treatment.Both groups of patients were treated for 3 courses of treatment.The therapeutic effects and cognitive dysfunction and daily living ability of the two groups were compared.Results The total effective rate of treatment in the control group and the observation group was 70.96%and 93.54%,respectively.The total effective rate of the control group was significantly lower than that of the observation group(P<0.05).There was no difference in the MMSE and MoCA scores between the two groups before treatment(P>0.05).After treatment,the patients of two groups significantly improved compared with that before treatment.The MMSE and MoCA scores in the observation group were significantly higher than those in the control group(P<0.05).Conclusion The effect of hyperbaric oxygen combined with edaravone in the treatment of patients with delayed encephalopathy caused by acute carbon monoxide poisoning is more significant,and it has more application value for improving the cognitive function and daily living ability of patients.
Keywords:Hyperbaric Oxygen  Edaravone  Acute Carbon Monoxide Poisoning  Delayed Encephalopathy
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