2型糖尿病患者餐后血脂影响因素研究

目的探讨2型DM患者餐后脂代谢异常的影响因素。方法30例2型DM患者正常饮食下测定早餐前后及中餐前后血脂、血糖、C-肽，对可能影响2型DM患者餐后脂代谢异常的因素进行分析。结果早、中餐后TG、C-肽水平均较餐前明显升高（P〈0．001），HDL—C水平较餐前有所降低（P〈0．001）；早餐前后PC升高水平明显大于中餐前后PG变化（P〈0．05），TG水平升高则略低于中餐前后（P〈0．001），HDL—C变化不大，但早餐后TC、LDL—C较餐前降低，而中餐后TC、LDL—C较餐前升高，两者差异有显著性（P〈0．001）。结论2型DM患者存在明显的餐后脂代谢紊乱，饮食中脂肪、碳水化合物比例不同会导致餐后血糖、血脂及C-肽水平的不同变化。

Study on influentialfactors for postprandial lipid metabolism in type 2 diabetic patients

Objective To Study the influenctial factors for postprandial lipid metabolism in type 2 diabetics. Methods Fasting and postprandial level of blood glucose, plasma lipid and C - P were measured in 30 type 2 diabetic patients after breackfast and lunch. Analysis were performed on influential factors or postprandial lipid levels in type 2 diabetic patients . Results The postprandial plasma tfiglycerides（TG） and plasma C - P level were significantly higher than those of fast levels, but the postprandial highdensity lipoprotein cholesterol（ HDL- C） level was decreased than that of fast level . As for the pastprandial Iowdensity lipoprotein cholesterol（ LDL- C） and total cholesterol （TC） level after breackfast, it was lower than that of fast level, but higher than that of fast level after lunch （ P 〈 0. 001 ）. Conclusions Postprandial plasma lipids level has remarkable correlation with fasting one. The propotions of fat and carhohydrate can cause different changes in postprandial blood glucose, serum C- Pand plasma lipid.