| 高效液相色谱法测定青藤碱血药浓度及药物动力学研究 |
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| 引用本文： | 罗顺德,蔡鸿生,张先州,潘细贵. 高效液相色谱法测定青藤碱血药浓度及药物动力学研究[J]. 中国中药杂志, 1992, 17(7): 424-426 |
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| 作者姓名： | 罗顺德 蔡鸿生 张先州 潘细贵 |
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| 作者单位： | 湖北医学院,武昌430060 |
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| 摘 要： | 用反相高效液相色谱外标法,测定单剂量(20mg/kg)静脉注射青藤碱后不同时间兔体内血药浓度,并用Marguardt法迭代拟合,结果符合二室模型。
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| 关 键 词： | 青藤碱 高效液相色谱 药代动力学 |
| 收稿时间： | 1991-09-27 |
Studies on Pharmacokinetics of Sinomenine by HPLC |
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| Lou Shunde,Cai Hongsheng,Zhang Xianzhou and Pan Xigui. Studies on Pharmacokinetics of Sinomenine by HPLC[J]. China Journal of Chinese Materia Medica, 1992, 17(7): 424-426 |
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| Authors: | Lou Shunde Cai Hongsheng Zhang Xianzhou Pan Xigui |
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| Abstract: | Pharmacokinetics of sinomenine in rabbit was studied by reverse-phase HPLC method. After iv injection of 20mg/kg of sinomenine to rabbits, the pharmacokinetic characteristics were found to fit a two-compartment open model. |
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| Keywords: | sinomenine HPLC pharmacokinetics |
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