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Neuronal hypertrophy and mast cells in histologically negative,clinically diagnosed acute appendicitis: a quantitative immunophenotypical analysis
Authors:Safeena Amber  Alka Mary Mathai  Ramadas Naik  Muktha R Pai  Suneet Kumar  Keerthana Prasad
Institution:(1) Department of Genetics and Pathology, Uppsala University Hospital, Uppsala, Sweden;(2) Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland;(3) Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland;(4) Department of Medicine, Karolinska Institute, Stockholm, Sweden;(5) Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland;(6) Department of Oncology, Radiology and Clinical Immunology, Uppsala University Hospital, Uppsala, Sweden
Abstract:

Introduction and Aim  

In about 20–25% of appendicectomies performed for clinically suspected acute appendicitis, definite morphological changes are lacking on histopathological examination. The present study was done to investigate whether any changes in neurons and mast cells could be detected in patients presenting with clinical acute appendicitis but found to have normal appendix at histopathology.
Keywords:
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