消炎镇痛及激素类药物影响正畸牙移动的研究现状

文献回顾性分析在正畸治疗过程中服用消炎止痛及激素类药物对正畸牙移动产生的影响。通过PubMed检索自1990年-2009年实验研究消炎止痛及激素类药物对牙齿移动速度影响的相关文献,从实验设计、正畸力大小及用药剂量等方面进行了分析。非甾体抗炎药可减缓正畸牙的移动,甾体抗炎药则对正畸牙的移动不产生影响,皮质激素、甲状腺激素等可加速正畸牙的移动,但其稳定性差。在正畸治疗过程中可以选择性使用药物治疗来减缓支抗牙的移动提高支抗,亦可通过药物治疗来加速正畸牙的移动,缩短正畸治疗时间,提高矫治效率。

The effect of anti-inflammatoryand hormone drugs on orthodontic tooth movement

The authors retrieve PubMed related literatures from 1990 to 2009 on the study of anti-inflammatory and hormone drugs on orthodontic tooth movement, and analyze the experimental design, magnitude of force applied during tooth movement and dose. In order to literature review on the effect of anti-inflammatory and hormone drugs on orthodontic tooth movement in orthodontic treatment process. The results show that non-steroidal anti-inflammatory drugs （NSAIDs） decrease orthodontic tooth movement, but non-NSAID analgesics has no effect on orthodontic tooth movement. Corticosteroid hormone and thyroid hormone have been shown to accelerate orthodontic tooth movement, but the stability is poor. The author conclud that in the orthodontic treatment process, drugs can be selectively used to slow the movement of anchorage tooth and improve the anchorage, or drug therapy is adopted to accelerate orthodontic tooth movement, shorten orthodontic treatment time, improve appliance efficiency.