2型糖尿病影响因素的病例对照研究

目的:分析2型糖尿病患者患病的相关危险因素,进一步探讨相应的预防控制措施。方法:采用病例对照研究的流行病学方法,选取124例2型糖尿病住院患者及125例在体检中心进行体检的无糖尿病者作为对照,用自行设计的调查问卷对两组人群进行问卷调查,同时进行体格检测。结果:有糖尿病家族史(OR=4.448)、主食以米为主(OR=21.165)、吸烟(OR=2.821)、睡眠质量差(OR=3.040)、有熬夜习惯(OR=7.235)、性格内向(OR=11.424)、SBP(OR=1.048)、焦虑(OR=4.106)、TC(OR=26.654)、DBiL(OR=2.208)是2型糖尿病发生的危险因素(OR>1,P<0.05);而饮茶(OR=0.159)、蔬菜摄入量(OR=0.964)则起保护作用(OR<1,P<0.05)。结论:2型糖尿病是多因素共同作用的结果,应采取综合措施加强2型糖尿病的防范工作。

Case-control study on the risk factors in patients with type 2 diabetes mellitus

Objective:To explore the risk factors associated with type 2 diabetes mellitus(T2DM) for providing scientific evidences for the disease control and prevention. Methods:By case-control study,we conducted epidemiological investigation in 124 type 2 diabetics on hospital basis and recruited 125 subjects confirmed healthy in the medical examination center controls,and carried out the survey on the two groups using self-programmed questionnaire and medical check-up on the total subjects. Results:Multivariate unconditional logistic regression analysis suggested that susceptible risk factors of T2DM were associated with family history of diabetes mellitus(OR=4.448),rice for staple foods(OR=21.165),smoking(OR=2.821),poor sleep quality(OR=3.040),habits of staying up late(OR=7.235),introverted personality(OR=11.424),SBP(OR=1.048),anxiety(OR=4.106),TC(OR=26.654) and DBiL(OR=2.208)(OR>1,P<0.05),whereas tea drinking(OR=0.159) and quantity of daily vegetable intake(OR=0.964) were positive effects(OR<1,P<0.05). Conclusion:Prevention of T2DM should be involved in comprehensive measures since this disease can be the results of multiple causative factors.