Role of lipoprotein-associated phospholipase A2 in atherosclerosis |
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| Authors: | Shahar Lavi Joerg Herrmann Ronit Lavi Joseph P. McConnell Lilach O. Lerman Amir Lerman |
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| Affiliation: | (1) Division of Cardiovascular Diseases, Mayo Clinic, Mary Brigh 4-523, 200 First Street SW, Rochester, MN 55905, USA |
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| Abstract: | ![]()
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a biomarker that can be used to assess the risk for cardiovascular disease and events. In addition to being a useful marker of a risk factor, several studies suggest that Lp-PLA2 has a pathophysiologic role in the atherosclerotic disease process. In this article, we review this aspect and its therapeutic implications. |
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