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| 中药复方当归饮子治疗慢性荨麻疹的系统评价 | |
| 引用本文： | 杨猛,潘延斌,方金菊,谭美乐,卢斌珠,吴玲艳,程秋梅,庞国栋,李建民. 中药复方当归饮子治疗慢性荨麻疹的系统评价[J]. 中国实验方剂学杂志, 2014, 20(13): 235-238 |
| 作者姓名： | 杨猛 潘延斌 方金菊 谭美乐 卢斌珠 吴玲艳 程秋梅 庞国栋 李建民 |
| 作者单位： | 广西医科大学研究生学院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000;广西医科大学第三附属医院, 南宁 530000 |
| 基金项目： | 广西壮族自治区科学技术厅基金（桂科攻1140003B-86） |
| 摘 要： | 目的： 系统评价中药当归饮子治疗慢性荨麻疹（chronic urticaria，CU）的有效性和安全性。 方法： 计算机检索 PubMed、Embase、Cochrane Central、CBM、CNKI、万方和VIP数据库，搜集当归饮子治疗CU的随机及半随机对照试验，检索时限均从各数据库建库至2013年5月。采用 RevMan5.2.5软件进行Meta分析，采用GRADE Profile3.6对结果的证据质量等级进行评价。 结果： 最终纳入15项试验，共1 358例患者。Meta分析结果显示，当归饮子治疗CU的治愈率、有效率均优于除咪唑斯汀外的常规抗组胺药物（conventional antihistamine，CA）；复发率、不良反应发生率均低于CA。 结论： 本系统评价结果显示，与CA相比，当归饮子有更高的治愈率和有效率，能降低复发率、不良反应发生率。但由于纳入文献质量较低，尚需高质量的多中心大样本随机双盲对照试验来验证。 |
| 关 键 词： | 当归饮子 慢性荨麻疹 系统评价 随机对照试验 |
| 收稿时间： | 2013-08-19 |
Systematic Review on Treatment of Chronic Urticaria with Chinese Herbal Compound Danggui Yinzi |
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| YANG Meng,PAN Yan-bin,FANG Jin-ju,TAN Mei-le,LU Bin-zhu,WU Ling-yan,CHENG Qiu-mei,PANG Guo-dong and LI Jian-min. Systematic Review on Treatment of Chronic Urticaria with Chinese Herbal Compound Danggui Yinzi[J]. China Journal of Experimental Traditional Medical Formulae, 2014, 20(13): 235-238 | |
| Authors: | YANG Meng PAN Yan-bin FANG Jin-ju TAN Mei-le LU Bin-zhu WU Ling-yan CHENG Qiu-mei PANG Guo-dong LI Jian-min |
| Affiliation: | Postgraduate School of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China;The Third Affiliated Hospital of Guangxi Medical University, Nanning 530000, China |
| Abstract: | Objective: To systematically review the efficacy and safety of Danggui Yinzi in treatment of chronic urticaria(CU). Method: PubMed, Embase, Cochrane Central, CBM, CNKI, WANFANG and VIP were searched to collect RCTs or CCTs from inception to May 2013.The Meta-analysis was conducted with Revman 5.2.5 software. GRADE Profile3.6 was used to evaluate the grade of the quality of evidence. Result: 15 articles involving 1 358 patients were included in the Meta-analysis. The Meta-analysis showed for the cure rate and efficient Danggui Yinzi was superior to conventional antihistamine(CA) except mizolastine;recurrence rate and incidence of adverse reactions were lower than the CA. Conclusion: The system review shows that compared with CA,Danggui Yinzi has higher cure rate and effective and it has low recurrence rate and low incident of adverse reactions. |
| Keywords: | Danggui Yinzi chronic urticaria systematic review randomized controlled trials |
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