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地龙抗血栓有效部位的提取方法初探
引用本文:张砾岩,李玲. 地龙抗血栓有效部位的提取方法初探[J]. 中成药, 2010, 32(5)
作者姓名:张砾岩  李玲
作者单位:新疆自治区中医医院,新疆,乌鲁木齐,830000
摘    要:
目的:考察地龙中抗血栓有效部位的提取方法。方法:分别用水和50%、70%、80%乙醇,渗漉,水提取、50%醇沉以及稀HCl和磷酸缓冲液提取物进行体外对兔血凝血酶原时间的影响和抗凝血酶作用试验。结果:从抗凝血试验看,地龙的乙醇渗漉液优于地龙的水提液。结论:以70%乙醇对地龙进行渗漉提取方法简便,适于工业化生产。

关 键 词:地龙  抗血栓有效部位  提取方法

Extraction of anti-thrombotic contituent from Earthworm (Pheretima)
ZHANG Li-yan , LI Ling. Extraction of anti-thrombotic contituent from Earthworm (Pheretima)[J]. Chinese Traditional Patent Medicine, 2010, 32(5)
Authors:ZHANG Li-yan    LI Ling
Affiliation:ZHANG Li-yan,LI Ling (Xinjiang Autonomous Region Hospital of Traditional Chinese Medicine,Urumqi 830000,China)
Abstract:
AIM: To investigate the extraction of anti-thrombotic contituent from Earthworm ( Pheretima). METHODS: The prothrombin time (PT)of rabbit blood and antithrombin of 14 samples that were extracted by different methods were determined in vitro. RESULTS: The sample that was percolated with 70% alcohol and the sample that was extracted by semi-bionic method were better than ones that were extracted by other methods. CONCLUSION: It is a simple and practicable method to percolate Earthworm with 70% alcohol.
Keywords:Earthworm  anti-thrombotic contituent  extraction  
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