肌钙蛋白I和肌红蛋白测定在心脏手术后的应用价值

目的：观察外科心脏手术患者术后不同时间内肌钙蛋白(cTnI)和肌红蛋白(Myo)浓度值的变化。评价其对判断心肌损伤程度的应用价值。方法：采用化学发光法测定心脏手术和对照组胸外科手术患者术后48h内血清的心肌肌钙蛋白和肌红蛋白浓度。结果：心脏手术组术后cTnI、Myo出现明显增高；对照组(胸外科手术)中Myo有不同程度升高，而cTnI不升高。结论：cTnI和Myo在判断心脏外科手术预后具有重要意义，而在判断心肌损伤程度上cTnI更具应用价值。

Applicable value of detecting cTnI and Myo in post cardiac operation

Objective :To observe the variations of serum concentration of cardiac tropnin I(cTnI) and myoglobin(Myo) in the patients after heart surgery operation at different time, and to evaluate the clinical value of cTnI and Myo in determining the extent of myocardial injury . Methods :The cases undergoing surgery operation were randomly divided into 2 groups and serum concentration of cTnI and Myo in heart operation group and in control group who were the thoracic surgery operation patients were measured by chemiluminescent immnoassay at 48h after operation. Results :Serum levels of cTnI and Myo in heart operation group increased significantly after operation.To a certain extent serum Myo of control group also increased but cTnI did not increase. Conclusions :It seems that cTnI and Myo have important significance to determine the prognosis of heart surgery operation ,whereas cTnI may play the more important role in evaluating myocardial injury.