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| 中药猫爪草免疫活性部位的筛选 | |
| 引用本文： | 胡泽开,苗明三,刘会丽. 中药猫爪草免疫活性部位的筛选[J]. 辽宁中医药大学学报, 2010, 0(3) |
| 作者姓名： | 胡泽开 苗明三 刘会丽 |
| 作者单位： | 开开援生制药股份有限公司;河南中医学院; |
| 基金项目： | 河南省高等学校创新人才培养工程项目(2004-23) |
| 摘 要： | 目的:利用化学与药理学相结合的方法,以药效学为指标,对猫爪草的免疫活性部位进行系统筛选。方法:以香菇多糖片作为阳性对照,对猫爪草的猫爪草多糖、石油醚提取部位、乙酸乙酯提取部位、乙醇提取部位的提取物采用正常小鼠,通过观察对小鼠腹腔巨噬细胞吞噬功能的影响、溶血素和溶血空斑形成的影响确定猫爪草的免疫活性部位,进行药理学筛选。结果:猫爪草多糖可使吞噬百分率、吞噬指数显著升高,可显著促进溶血素的形成。结论:猫爪草多糖为猫爪草的主要免疫活性部位。 |
| 关 键 词： | 猫爪草 提取部位 免疫活性 筛选 |
Study on Immunocompetence of the Active Constituent Extracted from Radix Ranunculi Ternati |
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| HU Ze-kai,,MIAO Ming-san,LIU Hui-li. Study on Immunocompetence of the Active Constituent Extracted from Radix Ranunculi Ternati[J]. Journal of Liaoning University of Traditional Chinese Medicine, 2010, 0(3) | |
| Authors: | HU Ze-kai MIAO Ming-san LIU Hui-li |
| Affiliation: | 1. Kaikai Yuansheng Pharmaceutical Co./a>;Ltd/a>;Gushi 465200/a>;Henan/a>;China/a>;2. Henan College of Traditional Chinese Medicine/a>;Zhengzhou 450008/a>;China |
| Abstract: | Objective: To determine the effects of the different parts of active constituent of Radix Ranunculi Ternati on immune function of experimental animal. Methods: Use the lentinan tablets and the blank control to select active constituent from Radix Ranunculi Ternati Polysaccharide(RRTP) and the materials extracted by light petroleum, ethyl acetate, ethanol by the way of pharmacology. After intragastric administration, the effects of polysaccharide and active constituent of Radix Ranunculi Ternati on phagocyto... |
| Keywords: | Radix Ranunculi Ternati polysaccharide immunocompetence select |
| 本文献已被 CNKI 等数据库收录！ | |