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我院质子泵抑制剂应用情况分析
引用本文:向倩,梁燕,张静,崔一民. 我院质子泵抑制剂应用情况分析[J]. 中国医院用药评价与分析, 2008, 8(3): 194-197
作者姓名:向倩  梁燕  张静  崔一民
作者单位:北京大学第一医院,北京市,100034
摘    要:
目的:调查目前临床上质子泵抑制剂(PPI)的给药方式,探讨常用给药方案的合理性:方法:统计2007年4月~9月半年内我院住院患者中服用PPI的情况:结果:临床上最常用的给药方式为1日2次,占给药方案的54.52%,其中93.3%(埃索美拉唑和奥美拉唑.20mg,bid)是应用于非幽门螺杆菌根除的其他适应证治疗。结论:本研究证明目前临床PPI给药方案与说明书中规定用法用量存在较大差异。

关 键 词:质子泵抑制剂  用药分析

Clinical Application of Proton Pump Inhibitors
XIANG Qian,LIANG Yan,CUI Yi-min. Clinical Application of Proton Pump Inhibitors[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2008, 8(3): 194-197
Authors:XIANG Qian  LIANG Yan  CUI Yi-min
Affiliation:(The First Hospital of Peking University, Beijing 100034, China)
Abstract:
OBJECTIVE: To investigate the direction for use and dosage of PPI and to discuss the rationality of their common dosage regimes. METHODS: The use of PPI in the inpatients in our hospital from Apr. l to Set. 30 in 2007 were analyzed statistically. RESULTS: 54.52% of the PPI were administered bid. Of which, 93.3% (esomeprazole and omeprazole 20mg bid) were used for indications other than Helicobacter pylori eradication. CONCLUSION: The dosage regimens of PPI are greatly different from that specified in drug package inserts.
Keywords:Proton pump inhibitors  Analysis of drug use
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