血清C反应蛋白在肝硬化腹水合并感染中的临床意义

目的探讨血清C反应蛋白（CRP）在肝硬化腹水合并感染中的临床意义。方法检测106例肝硬化患者CRP、WBC和GR百分率（GR％），计算合并感染和继发感染者各指标的阳性率。结果合并感染组和继发感染组CRP、WBC和GR％水平分别显著高于未合并感染组和无继发感染组（P〈0．01）；合并感染组和继发感染组抗感染治疗后3d和7d，三者水平分别显著低于抗感染治疗前和治疗后3d（P〈0．01）。治疗前、治疗后3d和治疗后7dCRP阳性率均显著高于WBC和GR％阳性率（P〈0．01）。结论检测CRP对肝硬化腹水患者感染的进展及抗感染疗效判断具有重要意义。

Clinical significance of C reactive protein in liver cirrhosis patients complicating infection with ascites

Objective To explore the clinical significance of serum C reactive protein(CRP) in liver cirrhosis patients complicating infection with ascites.Methods The levels of CRP,white blood cell(WBC) and granulocyte percent(GR%) in 106 patients with liver cirrhosis were determined,the positive percent was calculated in patients of infection-complicating and secondary infection.Results At infection-complicating group and secondary infection group,the levels of CRP,WBC and GR% were significantly higher than those at non-infection-complicating group and non-secondary infection group,respectively(P<0.01) After 3 and 7 days of anti-microbe therapy,the levels of CRP,WBC and GR% were remarkedly lower than those before therapy and after 3 days of therapy,respectively,at infection complicating group and secondary infection group(P<0.01).Before therapy,after 3 days and 7 days of therapy,the positive percent of CRP was markedly higher than that of WBC and GR%(P<0.01).Conclusions It is valuable for the change of CRP to evaluate the occlurence,development and therapeutical effect of infection in liver cirrhosis patients with ascites.