盐酸氨溴索雾化吸人辅助治疗新生儿肺炎临床观察

目的:探讨盐酸氨溴索雾化吸入辅助治疗新生儿肺炎的疗效.方法:将60例新生儿肺炎患儿随机分为两组各30例,对照组采用常规抗感染、吸氧、吸痰等治疗,治疗组在对照组常规治疗基础上给予氨溴索30 mg电动压缩雾化吸入,2～3次/d.结果:治疗组总有效率90.0％,明显优于对照组的63.3％(P＜0.01),治疗组血气分析恢复正常时间为(3.50±1.29)d、肺部啰音消失时间(6.23±2.31)d、住院天数(9.51±3.23)d,均较对照组的(6.12±2.35)d、(9.15±3.14)d、(11.00±4.67)d明显缩短,两组比较差异均有统计学意义(P＜0.01).结论:盐酸氨溴索雾化吸入辅助治疗新生儿肺炎具有良好疗效和安全性.

The Clinical Observation of Inhalation Ambroxol as Adjunctive Therapy in Neonatal Pneumonia

Objective: To investigate the curative effect of ambroxol hydrochloride supporting the treatment of neonatal pneumonia.Methods: Sixty cases of newborns undergoing pneumonia were randomly divided into two groups with 30 patients in each group.Conventional anti-infection,oxygen therapy,sputum suction were administered to the control group,and the therapy group was treated with inhalation ambroxol 30 mg,2~3 times/d,based on the conventional treatment.Results: The total effective rate of the treatment group(90.0%) was significantly higher than that of the control group(63.3%)(χ2=5.96,P<0.01),and the recovery time of blood gases parameters(3.50±1.29)days,the relief time of pulmonary rale(6.23±2.31)days,and the length of hospital-stay(9.51±3.23)days in the therapy group were significantly shorter than those in the control group [(6.12±2.35)days,(9.15±3.14)days,(11.00±4.67)days](P<0.01).Conclusions: The inhalation ambroxol is a safe and valid adjunctive therapy in neonatal pneumonia.