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Silencing the porcine iGb3s gene does not affect Galα3Gal levels or measures of anticipated pig‐to‐human and pig‐to‐primate acute rejection
Authors:James R. Butler  Nicholas J. Skill  David L. Priestman  Frances M. Platt  Ping Li  Jose L. Estrada  Gregory R. Martens  Joseph M. Ladowski  Matthew Tector  A. Joseph Tector
Affiliation:1. Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA;2. Department of Pharmacology, Oxford University, Oxford, UK
Abstract:
Keywords:CRISPR/Cas9  Galα  3Gal  iGb3s  isoglobo‐series glycosphingolipids  antibody binding  cytotoxicity
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