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四联疗法治疗上消化道溃疡的临床疗效
引用本文:卢慧勤,詹重明,薛红仙,王耕. 四联疗法治疗上消化道溃疡的临床疗效[J]. 中国临床药学杂志, 1999, 0(Z1)
作者姓名:卢慧勤  詹重明  薛红仙  王耕
作者单位:中国人民解放军第177医院药剂科,中国人民解放军第177医院药剂科,中国人民解放军第177医院内科,中国人民解放军广州医高专药剂教研室 广州510317,广州510315
摘    要:
目的:观察奥美拉唑与阿莫西林、呋喃唑酮、胶态果胶铋剂四联治疗上消化道溃疡的疗效.方法:采用随机分组平行对照法,全组共100例,对照组用奥美拉唑20mg/d,共4wk;治疗组(四联疗法)采用奥美拉唑20mg/d,阿莫西林500mg tid,呋喃唑酮200mg tid,胶态果胶铋剂100mg tid,共2wk.结果:溃疡痊愈率治疗组为100%,对照组为92.0%(P>0.05)IIP根除率治疗组为93.88%,对照组为28.57%(P
关 键 词:奥美拉唑  阿莫西林  呋喃唑酮  胶态果胶铋剂  胃十二指肠溃疡  疗效

Clinical curative effects of tetraple therapy in treatment of patients with duodenum ulcer and gastric ulcer
Lu Huiqiru,Wang Geng,Xue Hongxian,et al. Clinical curative effects of tetraple therapy in treatment of patients with duodenum ulcer and gastric ulcer[J]. Chinese Journal of Clinical Pharmacy, 1999, 0(Z1)
Authors:Lu Huiqiru  Wang Geng  Xue Hongxian  et al
Affiliation:Lu Huiqiru,Wang Geng,Xue Hongxian,et alDepartment of Pharmacy,First 177 Hospital ofPLA,Guangzhou 510317
Abstract:
AIM: To investigate clinical curative effects of omeorazole, amoxicillin, fura-zolidone, colloid pectin biagent in the treatment of 100 patients with duodenum ulcer(DU) and gastric ulcer(GU)by the method of parallel control in random groups. METHODS:In the control groups (omeprazole 20 mg/d),the course of treatment was 4 wk,in the treatment groups omeprazole 20 mg/d ,amoxicillin 500 mg tid .furazolidone 200 mg tid,colloid pectin bi-agent 100 mg tid )the course of treatment was 2 wk. RESULTS:The healing rate of DU and GU was 100% in the treatment groups and 92. 0% in the control groups(P>0. 05 ). Eradica-tion rate of HP was 93. 88% in the treatment groups and 28. 57% in the control groups(p< 0. 01). Obvious adverse reaction was not found in the treatment. The ventral gastralgia catabasis in the treatment group was shorter than that of control. CONCLUSION: Eradica-tion rate of HP are better in the treatment group than in the control groups. Two therapy of the healing rate of DU and GU are similar.
Keywords:omeprazole  amoxicillin  furazolidon  colloid pectin biagcnt  duodenum ulcer and gastric ulcer  curative effect
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