| Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflarnmatory factors |
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| 引用本文： | Li YUE,Hua WANG,Li-hua LIU,Yu-xian SHEN2,Wei WEIInstitute of Clinical Pharmacology,Anhui Medical University,Hefei 230032,China. Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflarnmatory factors[J]. Acta pharmacologica Sinica, 2004, 0(9) |
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| 作者姓名： | Li YUE Hua WANG Li-hua LIU Yu-xian SHEN2 Wei WEIInstitute of Clinical Pharmacology Anhui Medical University Hefei 230032 China |
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| 作者单位： | Li YUE，Hua WANG，Li-hua LIU，Yu-xian SHEN2，Wei WEIInstitute of Clinical Pharmacology，Anhui Medical University，Hefei 230032，China |
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| 基金项目： | ProjectsupportedbyNaturalScienceFoundationofAnhuiProvince,No01043901 |
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| 摘 要： | ![]()
AIM: To investigate the profile of endostatin on adjuvant arthritis (AA) and angiogenesis blockade in synovitis. METHODS: The model of rat AA was induced by injection of intradermal complete Freund's adjuvant (CFA). Hind paw volume of rat was measured by volume meter and the activities of interleukin-1 (IL-1) and IL-2 were measured by the assay of thymocytes proliferation. IL-1β and tumor necrosis factor-a (TNF-α) produced
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Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflarnmatory factors |
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| Li YUE,Hua WANG,Li-hua LIU,Yu-xian SHEN,Wei WEIInstitute of Clinical Pharmacology,Anhui Medical University,Hefei ,China. Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflarnmatory factors[J]. Acta pharmacologica Sinica, 2004, 0(9) |
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| Authors: | Li YUE Hua WANG Li-hua LIU Yu-xian SHEN Wei WEIInstitute of Clinical Pharmacology Anhui Medical University Hefei China |
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| Affiliation: | Li YUE,Hua WANG,Li-hua LIU,Yu-xian SHEN2,Wei WEIInstitute of Clinical Pharmacology,Anhui Medical University,Hefei 230032,China |
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| Abstract: | ![]()
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| Keywords: | rats experimental arthritis endostatin angiogenesis inhibitors cytokines |
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