冠状动脉成形术中正常参考段的血管内超声研究

目的　应用血管内超声研究冠心病介入治疗时“正常”参考段的病变情况。方法　 12 0例冠心病患者行介入治疗 ,术中血管内超声 (IVU S)评价造影显示正常的参考血管段。结果　 (1)冠状动脉造影显示“正常”的参考段仅10 .8%经 IVUS证实无明显病变 ;(2 )参考段平均面积狭窄百分比为 (4 2 .6± 11.9) % ,参考段狭窄程度与目标病变的狭窄程度呈轻度正相关 (r=0 .32 7,P<0 .0 0 1) ;(3)参考段的病变中纤维斑块及钙化斑块较少而脂质斑块较多。结论　造影显示的“正常”参考段冠状动脉常存在不同程度的粥样硬化病变。

Intravascular ultrasound study of "normal" coronary artery reference segments in coronary angioplasty

Objictive To evaluate the magnitude and patterns of atherosclerosis by intravascular ultrasound in angiographically “normal” reference segments in patients umdergoing coronary angioplasty. Methods Intravascular ultrasound was used to study angiographically “normal” reference segments in 120 patients who would undergo percutaneous coronary intervention for coronary artery disease. Results (1)Only 13(10.8%) of 120 angiographically “normal” reference segments were normal by intravascular ultrasound. (2)The mean percent cross-sectional narrowing of the reference segments was (42.6±11.9)%, and reference segment percent cross-sectional narrowing correlated slightly with the target lesion percent cross-sectional narrowing (r=0.327,P<0.001). (3)Reference segments contained less fibrotic and calcific plaque and proportionately more soft plaque elements.Conclusion Angiographically “normal” coronary artery reference segments usually exists a various of extent of atherosclerosis.