湘潭市2005—2008年377例肺结核中断治疗原因分析

目的分析结核病控制项目实施近4年以来,湘潭市肺结核患者中,不同样本人群中断治疗的原因,探索减少中断治疗的针对性对策。方法收集整理我市2005—2008年因各种原因中断治疗的肺结核患者共377例,对样本人群的人口、社会经济情况（包括样本的年龄、性别、收入水平、是否常住人口、医疗保险享受情况）以及样本的诊疗相关信息（包括患者的就医过程、不良反应发生情况）进行建模分析,分析导致中断／终止治疗的影响因素。结果湘潭市2005—2008年发生肺结核中断治疗情况的样本人群中。常住人口与流动性人口具有不同的人口、社会经济背景;中断治疗的影响因素集中表现为疾病相关知识的缺乏、严重的不良反应、以及经济困难与交通不便。数据建模分析结果显示,高知识水平、享受医疗保险成为中断治疗模型中的保护性因素,而严重不良反应以及年龄较大成为中断治疗模型中的危险性因素。结论针对湘潭市不同人口、社会经济背景的样本人群,分析其肺结核中断发生的各自影响因素,并制定有针对性的对策．有助于进一步提高我市肺结核病防治工作的成效。

Study on the Reasons of Treatment Interruption of 377 Tuberculosis Cases in Xiangtan from 2005 to 2008

Objective To explore the reasons of treatment interruption of anfi-tuberculofic therapy and countermeasure after the enforcement of Tuberculosis Control Project （2005-2008） in Xiangtan. Methods The data of 377 patients with treatment interruption of anti-tuberculotic therapy were collected.The modeling analysis was established by adopting the followed information ： social and economic status, age, gender, income, resident population or not, medical insurance status, treatment process of anti-tuberculotic therapy, adverse side effect. The reasons of treatment interruption were explored via the modeling analysis. Results The social and economic status of patients with treatment interruption of anti-tubereulotic therapy were different between the resident population and floating population. Lack of disease related knowledge, severe adverse side effect, economical failure and disadvantage of transport are the four main reasons for the treatment interruption. High knowledge level and medical insurance are two protective factors for the modeling analysis,and severe adverse side effect and old age are two risk factors. Conclution The effect of Tuberculosis Control Project will be increased via the exploration of exact reasons of treatment interruption of anti-tuberculotic therapy and enforcement of the countermeasure.