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| 碘充足地区妊娠晚期孕妇的碘营养状况及甲状腺功能 | |
| 引用本文： | 魏薇,桑仲娜,张淑芬,刘华,张桂芹,赵娜,谭龙,张万起. 碘充足地区妊娠晚期孕妇的碘营养状况及甲状腺功能[J]. 中国妇幼保健, 2011, 26(22): 3385-3388 |
| 作者姓名： | 魏薇 桑仲娜 张淑芬 刘华 张桂芹 赵娜 谭龙 张万起 |
| 作者单位： | 1. 天津医科大学公共卫生学院营养与食品卫生教研室(天津),300070 2. 河北沧州市海兴县医院妇产科 3. 河北省沧州市疾病预防控制中心地方病防治科 |
| 基金项目： | 国家自然科学基金资助项目〔No.30972465〕; 2009达能宣教青年基金项目 |
| 摘 要： | 目的:探讨碘充足地区妊娠晚期孕妇的碘营养状况及甲状腺功能。方法:收集174例妊娠晚期孕妇的空腹晨尿及静脉血,砷-铈催化分光光度法测定尿碘浓度,化学发光法测定游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)及敏感促甲状腺激素(sTSH),放射免疫分析法测定甲状腺过氧化物酶抗体(TPOAb)和甲状腺球蛋白抗体(TGAb)。结果:孕妇平均年龄(28.07±4.87)岁,尿碘中位数217.06μg/L,大部分(63.2%)孕妇碘营养状况适宜,部分个体处于碘缺乏(27.6%)和碘过量(9.2%)状态。TPOAb和TGAb阳性率分别为24.1%和3.4%,有4例(2.3%)患亚临床甲状腺功能减退。尿碘与FT3、FT及sTSH水平之间相关性差异均无统计学意义(P>0.05);不同尿碘水平孕妇的抗体阳性率差异无统计学意义(P>0.05);与TPOAb阴性孕妇相比,TPOAb阳性者FT3水平降低,sTSH和尿碘水平升高;与TGAb阴性孕妇相比,TGAb阳性者sTSH水平降低(P<0.05)。结论:该地孕妇整体碘水平适宜,但仍存在碘缺乏和过量的个体,甲状腺自身抗体阳性可能使孕妇甲状腺功能异常,故应加强孕期尿碘水平及甲状腺功能的监测。 |
| 关 键 词： | 碘营养 孕妇 甲状腺功能 甲状腺自身抗体 |
Iodine nutritional status and thyroid function of pregnant women during the third trimester of pregnancy in an iodine-sufficient area |
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| WEI Wei,SANG Zhong-Na,ZHANG Shu-Fen et al. Iodine nutritional status and thyroid function of pregnant women during the third trimester of pregnancy in an iodine-sufficient area[J]. Maternal and Child Health Care of China, 2011, 26(22): 3385-3388 | |
| Authors: | WEI Wei SANG Zhong-Na ZHANG Shu-Fen et al |
| Affiliation: | WEI Wei,SANG Zhong-Na,ZHANG Shu-Fen et al.Department of Nutrition and Food Hygiene,School of Public Health,Tianjin Medical University,Tianjin 300070,China |
| Abstract: | Objective:To explore the iodine nutritional status and thyroid function of pregnant women during the third trimester of pregnancy in an iodine-sufficient area.Methods:The morning-urine and venous blood samples of 174 pregnant women during the third trimester of pregnancy were collected,arsenic-cerium catalytic spectrophotometer was used to detect the content of iodine in urine,chemiluminescence was used to detect the levels of free triiodothyronine(FT3),free thyroxine(FT4) and sensitive thyroid-stimulating ... |
| Keywords: | Iodine nutrition Pregnant women Thyroid function Thyroid autoantibody |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |