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阴道B超监测不明原因反复自然流产患者排卵的临床意义
引用本文:王慧春,刘慧文,习艳霞,李颖.阴道B超监测不明原因反复自然流产患者排卵的临床意义[J].中国妇幼保健,2011(19):2973-2975.
作者姓名:王慧春  刘慧文  习艳霞  李颖
作者单位:北京市海淀区妇幼保健院生殖中心;
摘    要:目的:探讨阴道B超监测不明原因反复自然流产患者排卵的临床意义。方法:采用阴道B超观察96例不明原因反复自然流产患者的卵泡生长模式(观察组),同时进行性激素测定及子宫内膜病理组织学检查。对56例92个周期给予促排卵及黄体支持治疗,观察妊娠结局。选择90例因男性因素不孕的患者作为对照组。结果:观察组卵泡发育不良综合征(FMS)发生率为79.2%(107/135),对照组FMS发生率为29.5%(37/90),二者差异有统计学意义(P<0.05);观察组中有排卵者的黄体中期雌二醇(E2)及孕激素(P)水平均明显低于对照组(P<0.05),子宫内膜分泌不良的发生率亦明显高于对照组(P<0.001);56例92个周期的促排卵及黄体支持治疗后共有48例妊娠,周期妊娠率52.1%(48/92),活产率为33.3%(42/56)。结论:卵泡发育不良是导致反复自然流产的病因之一;B超监测卵泡发育是诊断卵泡发育不良准确而有效的方法;在促排卵或黄体支持治疗中进行卵泡监测可预防再次发生自然流产。

关 键 词:不明原因反复自然流产  卵泡监测  卵泡发育不良综合征

Diagnostic and therapeutic significance of follicular development detected with B ultrasound among unexplained recurrent miscarriage
WANG Hui-Chun,LIU Hui-Wen,XI Yan-Xia,et al..Diagnostic and therapeutic significance of follicular development detected with B ultrasound among unexplained recurrent miscarriage[J].Maternal and Child Health Care of China,2011(19):2973-2975.
Authors:WANG Hui-Chun  LIU Hui-Wen  XI Yan-Xia  
Institution:WANG Hui-Chun,LIU Hui-Wen,XI Yan-Xia,et al..Department of Reproduction,Maternal and Fetal Hospital of Haidian,Beijing 100080,China
Abstract:Objective:To investigate the diagnostic and therapeutic significance of follicular development detected with vaginal ultrasound among unexplained recurrent miscarriage by follicular maldevelopment syndrome(FMS)..Methods:The follicular development was detected by vaginal ultrasound and the concentration of sex hormone was determined in 96 patients with history of unexplained recurrent miscarriage..Among them progestogen measurement and endometrial biopsy in luteal phase were performed..92 cycles of ovulation...
Keywords:Unexplained recurrent miscarriage  Follicular detection  Follicular maldevelopment syndrome  
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