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| 窒息新生儿凝血功能状态检测及临床意义 | |
| 引用本文： | 赵捷,庄思齐. 窒息新生儿凝血功能状态检测及临床意义[J]. 中国妇幼保健, 2011, 26(18): 2765-2766 |
| 作者姓名： | 赵捷 庄思齐 |
| 作者单位： | 1. 广东省深圳市妇幼保健院新生儿科,518020 2. 中山大学第一附属医院 |
| 摘 要： | 目的:探讨窒息新生儿凝血相关指标的改变及临床意义,为临床早期干预异常的凝血象提供依据。方法:将276例新生儿分为4组,即正常足月儿(70例)、窒息足月儿(65例)、无窒息早产儿(77例)、窒息早产儿(62例)。在出生后24h内分别检测凝血酶原时间(PT)、部分凝血活酶时间(APTT)、纤维蛋白原(Fg)、凝血酶时间(TT)和D-二聚体等5项指标。结果:窒息足月儿与正常足月儿PT、APTT、Fg、TT比较差异无统计学意义,但窒息足月儿D-二聚体升高,两组比较差异有统计学意义(P<0.01)。与无窒息早产儿比较,除TT外,窒息早产儿PT、APTT均延长,D-二聚体升高,Fg降低(P<0.05);与窒息足月儿比较,窒息早产儿PT、APTT、TT均延长,D-二聚体升高,Fg降低(P<0.01)。结论:窒息足月儿大都存在以高凝为特征的前DIC或DIC早期,窒息早产儿更容易发生DIC。 |
| 关 键 词： | 窒息 新生儿 凝血 弥散性血管内凝血 |
Detection and clinical significance of coagulant function of neonates with asphyxia |
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| ZHAO Jie,ZHUANG Si-Qi. Detection and clinical significance of coagulant function of neonates with asphyxia[J]. Maternal and Child Health Care of China, 2011, 26(18): 2765-2766 | |
| Authors: | ZHAO Jie ZHUANG Si-Qi |
| Affiliation: | ZHAO Jie,ZHUANG Si-Qi.Department of Neonatology,Shenzhen Maternal and Child Health Hospital,Shenzhen 518020,Guangdong,China |
| Abstract: | Objective:To explore the change of coagulation related indexes and its clinical significance in neonates with asphyxia,provide a basis for clinical early intervention of abnormal blood coagulation.Methods:276 neonates were divided into 4 groups:normal full term infants(70 neonates),asphyxial full term infants(65 neonates),non-asphyxial premature infants(77 neonates) and asphyxial premature infants(62 neonates).Five indexes including prothrombin time(PT),activated partial prothrombin time(APTT),fibrinogen(Fg... |
| Keywords: | Asphyxia Neonate Coagulation DIC |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |