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未成熟树突状细胞防治移植排斥反应的研究
引用本文:徐全晓,吴广胜. 未成熟树突状细胞防治移植排斥反应的研究[J]. 医学综述, 2008, 14(1): 21-23
作者姓名:徐全晓  吴广胜
作者单位:石河子大学医学院第一附属医院血液科,新疆,石河子,832008
基金项目:石河子大学校科研和教改项目
摘    要:未成熟树突状细胞在诱导移植免疫耐受,防治移植排斥反应方面中的作用,已成为目前器官移植领域研究的热点,并且得以充分肯定。在实验动物模型中,利用未成熟树突状细胞诱导特异性免疫耐受,防治移植排斥反应,取得了理想的效果。仅就未成熟树突状细胞的生物学特性、培养、诱导免疫耐受的机制、防治移植排斥反应的研究进行综述。

关 键 词:未成熟树突状细胞  免疫耐受  移植排斥反应
文章编号:1006-2084(2008)01-0021-03
收稿时间:2007-04-12
修稿时间:2007-12-06

Research Progress of Immature Dendritic Cells in Preventing and Treating Graft Rejective Reaction
XU Quan-xiao,WU Guang-sheng. Research Progress of Immature Dendritic Cells in Preventing and Treating Graft Rejective Reaction[J]. Medical Recapitulate, 2008, 14(1): 21-23
Authors:XU Quan-xiao  WU Guang-sheng
Affiliation:XU Quan-xiao, WU Guang-sheng. ( Department of Hematopathy , First Affiliated Hospital, Medical College of Shihezi University, Shihezi 832008, China)
Abstract:The role of immature dendritic cells inducing transplantation immunological tolerance and preventing as well as treating graft rejective reaction had become the hot spot in the study of organ transplantation at present,which also had enough affirmation.In the experimental animal model,the prevention and therapy of graft rejectve reaction by using immature dendritic cells to induce specific immunological tolerance had achieved satisfactory outcome.This article reviews immature dendritic cells about its biological feature,culture,mechanism of immunological tolerance induction and studies to prevent and treat graft rejective reaction.
Keywords:Immature dendritic cell  Immune tolerance  Graft rejection reaction
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