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| 干细胞样细胞在乳腺良恶性病变中的数量与分布 | |
| 引用本文： | 吕新全,索振河,马长路,赵阿红,宋一民,李惠翔. 干细胞样细胞在乳腺良恶性病变中的数量与分布[J]. 临床与实验病理学杂志, 2008, 24(4) |
| 作者姓名： | 吕新全 索振河 马长路 赵阿红 宋一民 李惠翔 |
| 作者单位： | 郑州大学第一附属医院病理科,河南省肿瘤病理重点实验室,郑州,450052;郑州大学第一附属医院病理科,河南省肿瘤病理重点实验室,郑州,450052;郑州大学第一附属医院病理科,河南省肿瘤病理重点实验室,郑州,450052;郑州大学第一附属医院病理科,河南省肿瘤病理重点实验室,郑州,450052;郑州大学第一附属医院病理科,河南省肿瘤病理重点实验室,郑州,450052;郑州大学第一附属医院病理科,河南省肿瘤病理重点实验室,郑州,450052 |
| 摘 要： | 目的 探讨乳腺上皮干细胞样细胞(stem-like cells,SIC)在乳腺部分良恶性病变中的数量及分布.方法 使用免疫组化双染法检测了89例乳腺良性病变及36例乳腺浸润性导管癌(invasive ductal carcinoma,IDC)中SLC的密度及分布部位.结果 ①SLC在良性病变中主要分布于乳腺腺管的腔面顶层上皮和肌上皮细胞之间;②在实质增生区SLC密度多于纤维腺瘤及实质减少区(P<0.05);③MUC-/ESA 细胞在IDC中数量差异较大.结论 SLC的数量及分布随病变不同而异. |
| 关 键 词： | 乳腺上皮干细胞 乳腺良性病变 乳腺肿瘤浸润性导管癌 免疫组化双染法 |
Expression of mammary epithelial stem-like cells in breast benign and malignant lesions |
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| L Xin-quan,SUO Zhen-he,MA Chang-lu,ZHAO A-hong,SONG Yi-min,LI Hui-xiang. Expression of mammary epithelial stem-like cells in breast benign and malignant lesions[J]. Chinese Journal of Clinical and Experimental Pathology, 2008, 24(4) | |
| Authors: | L Xin-quan SUO Zhen-he MA Chang-lu ZHAO A-hong SONG Yi-min LI Hui-xiang |
| Affiliation: | Department of Pathology;First Affiliated Hospital of Zhengzhou University;the Tumor Pathology Key Laboratory of Henan Province;Zhenzhou 450052;China |
| Abstract: | Purpose To investigate the expression of the mammary epithelial stem-like cells (SLC) in breast benign and malignant lesions. Methods The number and distribution of SLC in 89 cases of breast benign diseases and 36 cases of breast invasive ductal carcinoma (IDC) were examined by immunohistochemical double staining method. Results Most of SLC were located between luminal apical epithelia and myoepithelia. SLC in parenchymal hyperplastic areas was more than that in parenchymal hypoplastic areas and in fibroade... |
| Keywords: | mammary epithelial stem cell breast lesion immunohistochemical double staining |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |