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rIL-2/LAK细胞治疗晚期恶性肿瘤
引用本文:张月桂 尤庆山. rIL-2/LAK细胞治疗晚期恶性肿瘤[J]. 肿瘤防治研究, 1995, 22(1): 12-13
作者姓名:张月桂 尤庆山
作者单位:1. 黑龙江省肿瘤研究所;
2. 黑龙江省肿瘤医院
摘    要:
 胎儿来源的LAK细胞/rIL-2对5例失去手术、化疗、放疗机会的晚期恶性肿瘤病人进行了过继免疫治疗。结果都取得了-定的疗效,黑色素瘤病人肺转移结节基本消失,局部瘤细胞全部坏死,组织细胞正常;淋巴瘤病人转移灶消退59%;小肠平滑肌肉瘤病人在没进行此疗法之前2年半复发、手术三次。第三次手术后用此疗法治疗-个疗程,三年后第-次复发。为晚期恶性肿瘤病人延长了生命,提高了生存质量争得了再次治疗的机会。

关 键 词:基因重组 白细胞介素2 癌 免疫疗法 LAK细胞

Treatment of Patients with Advanced Malibnant Tumor by Transfor LAK Cells Combined with rIL-2
Zhang Yuegui. Treatment of Patients with Advanced Malibnant Tumor by Transfor LAK Cells Combined with rIL-2[J]. Cancer Research on Prevention and Treatment, 1995, 22(1): 12-13
Authors:Zhang Yuegui
Affiliation:Cancer Institute: Helongjiang Harbin 150040
Abstract:
Five advanced malignant tumor were treated with LAK cells isolated from human fetal spleen combined with rIL-2. One patient with malignant melanoma had metastasis tumor dispeared in one lung and significantly reduced in the other. The matastasis lesion of one patient with lymphoma de-creased 59% after treatment, a patient with intestinal smooth muscle sarcoma had prolonged relapse by administrated LAK/rIL-2" NO serious effects were observed. The results indicated that LAK/ rIL-2 in the treatment of patient with advanced malignant tumor is effect and safe.
Keywords:Lymphoma-activated kill cell (LAK cell)  Recombined interleukin-2 (rIL-2)  Fetal  Immunotberapy
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