食管癌术后早期肠内营养的临床应用

目的:探讨食管癌术后早期肠内营养的安全性、可行性和临床疗效。方法:选择86例食管癌手术患者。随机分为肠内营养组(EN组n=55)和肠外营养组(PN组n=31),所有病例在术前及术后第1、8天分别测血清总蛋白、白蛋白、前白蛋白、转铁蛋白、淋巴细胞计数、尿素氮、肌酐、血糖、谷丙转氨酶、血红蛋白和电解质(K+、Na+)。临床观察营养支持后有无消化道症状,胃肠功能恢复情况,有无吻合口瘘及测体质量。结果:所有病例在研究期间无死亡、无明显肝肾功能改变、无吻合口瘘。营养支持后EN组白蛋白、前白蛋白、转铁蛋白等水平明显升高(P<0.01)。营养支持后EN组与PN组对比,白蛋白、前白蛋白、转铁蛋白和淋巴细胞计数明显增高(P<0.01)。临床观察生命体征及肛门恢复排气时间较PN组显著缩短时间(P<0.01)。结论:食管癌术后早期肠内营养安全可行,既能改善营养状态,维护和促进胃肠道功能,又能提高机体免疫功能,减少术后并发症的发生。

The clinical application of postoperative early enteral nutrition in patients with esophagea cancer

Objective:To evaluate the effects of early enteral nutrition app lied in patientswith esophageal cancer.Methods:86 patientswith esophageal cancer undergone radical resection and reconstruction were randomly allocated into 2 group s(Entoral-Nutrition group,EN group,n =55 and Parentoral-Nutrition group,PN group n = 31).Serum concentrations of albumin,prealbumin were examined before operation and on the 8 th postoperative day;the electrolytes and nutritional status were observed;the postoperative comp lication...