短期胰岛素泵强化治疗对初发2型糖尿病的疗效观察

目的了解短期胰岛素泵强化治疗对初发2型糖尿病的临床疗效及其影响因素。方法34例初发的2型糖尿病经胰岛素泵强化治疗2周，治疗前后行空腹血糖、餐后血糖、糖化血红蛋白、血尿C肽、体重指数等测定，以评价治疗效果。结果2周的强化胰岛素泵治疗能有效及平稳地降低血糖，与治疗成功组相比，病程越短，胰岛素用量越少，达标时间越短，其临床缓解率的越高。结论短期的胰岛素泵强化治疗能使初诊的2型糖尿病患者血糖达到有效控制，部分患者不用药物，仅通过饮食控制就可获得良好的血糖控制。

Treated newly diagnosed type 2 diabetes patients with short-term continuous subcutaneous insulin

Objective To evaluate the clinical efficacy of short-term intensive treatment in newly diagnosed type 2 diabetes patient. Methods Thirty-four newly diagnosed type 2 diabetes patient were treated with continuous subcutane- ous insulin infusion （CSII） for 2 weeks. The changes of fasting blood glucose （FBG）, 2-hour postprandial blood glucose （PB2h）, glycosylated hemoglobin （HbAlc） , C-peptide（C-p） and body mass index （BMI） were assessed before and after CSII intensive insulin treatment. Results The excellent glycemic control in all patients with CSII were rapid and stable. The course of disease was short, and the dosage of insulin was less and the success rate was high in patients with CSII, compared with patients with conventional methods. Conclusion Short-term CSII intensive therapy can effectively induce long-term good glyeemic control without medication in newly diagnosed type 2 diabetes patients.