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| 非小细胞肺癌分子靶向治疗的现状及进展 | |
| 引用本文： | 王敏,刘荣玉. 非小细胞肺癌分子靶向治疗的现状及进展[J]. 国际呼吸杂志, 2011, 31(8): 637-640. DOI: 10.3760/cma.j.issn.1673-436X.2011.008.018 |
| 作者姓名： | 王敏 刘荣玉 |
| 作者单位： | 安徽医科大学第一附属医院老年呼吸内科,合肥,230032 |
| 摘 要： | 非小细胞肺癌是一种常见的恶性肿瘤,化学治疗的疗效似已达到平台,而分子靶向治疗以其符合生理、低毒和理论上高效的特点,越来越成为晚期非小细胞肺癌治疗的热点.文章就分子靶向治疗的作用靶点包括表皮生长因子受体、血管内皮因子受体,还有最近发现的EML4-ALK等进行综述,以展示分子靶向药物对于晚期非小细胞肺癌治疗的良好前景. |
| 关 键 词： | 非小细胞肺癌 分子靶向治疗 表皮生长因子受体 血管内皮因子生长受体 |
Status and progress on molecular targeted therapy in non-small cell lung cancer |
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| WANG Min,LIU Rong-yu. Status and progress on molecular targeted therapy in non-small cell lung cancer[J]. International Journal of Respiration, 2011, 31(8): 637-640. DOI: 10.3760/cma.j.issn.1673-436X.2011.008.018 | |
| Authors: | WANG Min LIU Rong-yu |
| Abstract: | Non-small cell lung cancer is a common malignant tumor, the efficacy of chemotherapy has reached a plateau, and the molecular targeted therapy characterized by low toxicity and high efficiency has increasingly become a focus of treatment of advanced non-small cell lung cancer. This paper reviews the targets of molecular targeted therapy, including epidermal growth factor receptor, vascular endothelial growth factor receptor, as well as EML4-ALK recently discovered,etc. to show the good prospects ofmolecular targeted drugs for the treatment of advanced non-small cell lung cancer. |
| Keywords: | Non-small cell lung cancer Molecular targeted therapy Epidermal growth factor receptor Vascular endothelial growth factor receptor |
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