过敏性结膜炎与干眼症的相关性临床分析

目的通过对过敏性结膜炎的泪膜功能变化的观察,分析其与干眼症之间的相关性。方法选取江苏省江阴市人民医院2013年1月至2013年6月门诊诊断为过敏性结膜炎者42例(84只眼)为观察组,正常者42例(84只眼)为对照组,分别进行裂隙灯检查、泪膜破裂时间(break-up time,BUT)检查、角膜荧光素染色试验(fluorescein,FL)、基础泪液分泌试验(schirmer I test,SIt)。所有受检对象年龄、性别之间不存在统计学差异,且排除全身及其他眼表疾患。结果过敏性结膜炎患者的泪膜功能都存在不同程度的异常,SIt、BUT、FL三项指标与对照组之间相比均存在显著的统计学差异(P<0.05)。结论过敏性结膜炎会导致泪膜稳定性降低,导致干眼症的发生。

Clinical Analysis of the Relationship between Allergic Conjunctivitis and Dry Eye

Objeetive To investigate the change of the tear film function in allergic conjunctivitis and to analyzed the correlation with dry eye. Methods 42 patients （84 eyes） with allergic conjunctivitis from January to June in 2013 were taken as the observation group and 42 normal people （84 eyes） were taken as control group. Slit lamp examination, tear film break-up time （break-up time, BUT） examination corneal fluorescein staining test （fluorescein, FL） and Schirmer I test（Sit） were performed respectively. There is no significant difference between the genders and the age.All the subjects were exclusion of systemic and other ocular disorders. Results The patients with allergic conjunctivitis have different degrees of tear film abnormalities, compare with control group the Sit, BUT and FL,has significant statistically difference（P〈0.05）. Conclusion The allergic conjunctivitis decrease the stability of the tear film, and also lead to dry eye.