胰十二指肠切除术后腹腔感染的危险因素分析

目的 分析胰十二指肠切除术后腹腔感染发生的危险因素.方法 回顾性分析我院1994年1月至2008年1月101例胰十二指肠切除术患者的临床资料,分析影响腹腔感染发生的危险因素.结果 腹腔感染的发生率为12.9%(13/101);单变量分析结果 表明胰胆肠瘘、术后肺炎、术前急性胆管炎、胰腺质地是腹腔感染发生的危险因素(P<0.05),多因素Logistic回归分析结果 表明胰胆肠瘘、术后肺炎、术前急性胆管炎是腹腔感染发生的独立危险因素,相对危险度(OR)分别为11.914、9.891和7.197.结论 胰胆肠瘘、术后肺炎、术前急性胆管炎是胰十二指肠切除术后腹腔感染发生的危险因素,积极防治胰胆肠瘘、术后肺炎、术前急性胆管炎可降低腹腔感染发生率.

Analysis of risk factors for intra-abdominal infection after pancreaticoduodenectomy

Objective To study the risk factors for intra-abdominal infection after pancreaticoduodenecto-my. Methods Clinical data of 101 cases undergoing pancreaticoduodenectomy in our hospital from January 1994 to January 2008 were reviewed retrospectively. The risk factors were analyzed. Results The incidence of intra-abdomi-hal infection was 12.9% (13/101). Univariate analysis showed postoperative pancreatic,biliary and intestinal fistu-la,pulmonary infection,preoperative acute cholangitis and texture of the remnant pancreas were the risk factors for intra-abdominal infection(P<0.05). Multivariate Logistic regression revealed that postoperative pancreatic, biliary and intestinal fistula, pulmonary infection, preoperative acute cholangitis were independent risk factors (OR = 11.914,9.891 and 7.197 ) of intra-abdominal infection after pancreaticoduodenectomy. Conclusion Preventing and curing pancreatic ,biliary and intestinal fistula, pulmonary infection, preoperative acute cholangitis can decrease the incidence of intra-abdominal infection.