43例会阴部赘生物的形态观察及人乳头状瘤病毒抗原的检测

对43例会阴部乳头状赘生物进行形态学观察及人乳头状瘤病毒抗原(HPV—AS)的检测,结果诊断为尖锐湿疣(CA)29例(67.4％),其中HPV—Ag阳性24例(82.8％);湿疣样病变14例(32.6％),HPV—Ag均为阴性。赘生物肉眼分两型,第Ⅰ型菜花或鸡冠状,17例全为CA,具有典型的空泡细胞等组织相,其中15例HPV—Ag阳性;第Ⅱ型细乳头状26例,其中12例具有典型CA组织相,9例HPV—Ag阳性。另14例切片中无空泡细胞而见空泡样细胞,HPV—Ag全为阴性,诊断为湿疣样病变。

Morphologic Observation and Detection of Human Papillomavirus Antigen in 43 Cases Perineum Vegetation

Morphology and expression of human papillomavirus antigen (HPH-Ag)of 43 cases of papillary vegetation in the perineum were studied. The results suggested that 29 cases (67. 4%) were diagnosed as condyloma acuminatum,24 cases (82. 8%) were positive PHV-Ag,and 14 cases (32. 6%)were condyloma-like lesions and expressed negative PHV-Ag. Macroscopically, the vegetations can be divided into two types. The typel(17 cases) fromed cauliflower-like or cock'scomb-like masses and showed classic kilocytotic cells microscopically. The condylome acuminatum were considered and 15 cases positive PHV-Ag were detected in all cases of type I. The type II(26 cases) appeared as usually fine papillary growths; 12 cases of them were condyloma acuminatum. The positive rate of PHV-Ag was 75% The remainder (14 cases) of type II were condyloma-like lesions (53. 8%),and showed kiolocyte-like cells other than typical kioloytic cells as well as HPVAg negative expression.