| Peutz-Jeghers综合征的诊治进展和预防性治疗 |
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| 引用本文： | 魏学明,顾国利,徐丽梅,毛高平,王石林. Peutz-Jeghers综合征的诊治进展和预防性治疗[J]. 世界华人消化杂志, 2011, 0(30): 3111-3116 |
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| 作者姓名： | 魏学明 顾国利 徐丽梅 毛高平 王石林 |
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| 作者单位： | 中国人民解放军空军总医院普通外科;中国人民解放军空军总医院康复科;中国人民解放军空军总医院消化内科; |
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| 摘 要： | Peutz-Jeghers综合征(Peutz-Jeghers syndrome,PJS)以皮肤黏膜色素斑、胃肠道错构瘤息肉和遗传性为临床特征.PJS胃肠道息肉可产生梗阻、出血、套叠、恶变等严重并发症,目前其临床治疗以手术和内镜治疗为主,其中双气囊电子小肠镜对于PJS胃肠道息肉的诊断和治疗具有重要的临床意义.随着转化医学...
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| 关 键 词： | Peutz-Jeghers综合征 胃肠道息肉 治疗 诊断 转化医学 |
Advances in the prevention,diagnosis and treatment of Peutz-Jeghers syndrome |
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| Xue-Ming Wei,Guo-Li Gu,Shi-Lin Wang. Advances in the prevention,diagnosis and treatment of Peutz-Jeghers syndrome[J]. World Chinese Journal of Digestology, 2011, 0(30): 3111-3116 |
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| Authors: | Xue-Ming Wei Guo-Li Gu Shi-Lin Wang |
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| Affiliation: | Xue-Ming Wei,Guo-Li Gu,Shi-Lin Wang,Department of General Surgery,Air Force General Hospital of Chinese PLA,Beijing 100142,China Li-Mei Xu,Department of Rehabilitation,China Gao-Ping Mao,Department of Gastroenterology,China |
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| Abstract: | Peutz-Jeghers syndrome (PJS) is an autosomal dominant inherited disease caused by inactivating germline mutations of the LKB1/STK11 gene and characterized by mucocutaneous pigmentation,multiple gastrointestinal hamartomatous polyps and family history.Life-threatening complications include intestinal obstruction and an increased risk for developing gastrointestinal malignancies and extraintestinal cancers.Surgery and endoscopic therapy are still main ways to manage gastrointestinal polyposis in PJS patients,... |
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| Keywords: | Peutz-Jeghers syndrome Gastrointestinal polyposis Therapy Diagnosis Translational medicine |
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