|
|||||
|
|
| Wnt途径及其拮抗剂与肿瘤的关系 | |
| 引用本文： | 辛芝,战忠利. Wnt途径及其拮抗剂与肿瘤的关系[J]. 国际病理科学与临床杂志, 2007, 27(1): 7-31 |
| 作者姓名： | 辛芝 战忠利 |
| 作者单位： | 天津医科大学附属肿瘤医院病理科,天津,300060;天津医科大学附属肿瘤医院病理科,天津,300060 |
| 摘 要： | Wnt途径是重要的细胞信号转导途径，在细胞的增殖、分化中发挥重要作用。Wnt途径的异常与多种肿瘤的发生或转移有关。而Wnt拮抗剂则可以拮抗Wnt途径。因此深入研究Wnt信号通路及其拮抗剂，设计出阻断Wnt通路的物质，可为将来肿瘤的治疗提供一种可行性的途径。 |
| 关 键 词： | Wnt Wnt拮抗剂 肿瘤形成 |
| 文章编号： | 1673-2588(2007)01-0028-04 |
| 收稿时间： | 2006-09-10 |
| 修稿时间： | 2006-09-10 |
Wnt signaling and Wnt antagonist in tumorigenesis |
|
| XIN Zhi,ZHAN Zhong-li. Wnt signaling and Wnt antagonist in tumorigenesis[J]. Journal of International Pathology and Clinical Medicine, 2007, 27(1): 7-31 | |
| Authors: | XIN Zhi ZHAN Zhong-li |
| Affiliation: | Department of Pathology, Tumor Hospital, Tianjin Medical University, Tianjing 300060, China |
| Abstract: | Wnt signaling is one of the major cell signalings and plays an important role in proliferation and differentiation of cells.Abnormal Wnt signaling involves with many tumors. Wnt antagonists can act as negative regulators of Wnt signaling. It deserves further study on the components of the Wnt pathway and its antagonists to provide valuable targets for potential anti-cancer therapeutic agents. |
| Keywords: | Wnt Wnt antagonists tumorigenesis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
| 点击此处可从《国际病理科学与临床杂志》浏览原始摘要信息 | |
| 点击此处可从《国际病理科学与临床杂志》下载免费的PDF全文 | |