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| 检测CD44v6在涎腺肿瘤表达的病理意义和技术要点 | |
| 引用本文： | 秦蓉晖,程斌,陈小华. 检测CD44v6在涎腺肿瘤表达的病理意义和技术要点[J]. 中山大学学报(医学科学版), 2000, 21(4): 316-317 |
| 作者姓名： | 秦蓉晖 程斌 陈小华 |
| 作者单位： | 中山医科大学口腔医学院!广东广州510055 |
| 基金项目： | 广东省科委重点科技攻关项目!(970050) |
| 摘 要： | :【目的】确定CD44v6在涎腺肿瘤性上皮细胞的表达特点及其病理意义。【方法】应用免疫组织化学染色 ,检测CD44v6在正常涎腺、多形性腺瘤、腺样囊性癌等良恶性肿瘤组织中的表达。【结果】CD44v6在闰管储备细胞分化的肿瘤性上皮细胞表达 ,而在排泄管储备细胞分化的肿瘤性上皮细胞阴性表达。【结论】CD44v6有助于了解涎腺肿瘤细胞的组织学来源 |
| 关 键 词： | CD44v6 涎腺肿瘤/病理学 免疫组织化学 |
| 修稿时间： | 1999-12-31 |
Pathological Significance and Technique for Detection of CD44v6 Expression in Salivary Gland Tumors |
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| QIN Rong hui,CHENG Bin,CHEN Xiao hua,LI Ru yao. Pathological Significance and Technique for Detection of CD44v6 Expression in Salivary Gland Tumors[J]. Journal of Sun Yatsen University(Medical Sciences), 2000, 21(4): 316-317 | |
| Authors: | QIN Rong hui CHENG Bin CHEN Xiao hua LI Ru yao |
| Abstract: | Objective To investigate the characteristics and pathological significance of CD44v6 expression in epithelial cells of salivary gland tumors. Method Immunohistochernical technique was used to detect CD44v6 expression in tissues of normal salivary gland and some benign or malignant tumors such as pleomorphic adenoma and adenoid cystic carcinoma. Results The expression of CD44v6 was positive in neoplastic epithelial cells differentiated from intercalated duct reserve cells but it was negative in epithelial cells differentiated from excretory duct. Conclusion CD44v6 expression can be used to reveal the histogenesis of salivary gland tumors. |
| Keywords: | CD44v6 salivary gland neoplasms/pathology immunohistochemistry |
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