| 齐拉西酮与奥氮平治疗精神分裂症对照研究 |
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| 引用本文： | 陈贻华,ZHANG Wen-wei,黄海峰,CHEN Bing-rong,陈振杰. 齐拉西酮与奥氮平治疗精神分裂症对照研究[J]. 临床精神医学杂志, 2008, 18(4): 267-268 |
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| 作者姓名： | 陈贻华 ZHANG Wen-wei 黄海峰 CHEN Bing-rong 陈振杰 |
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| 作者单位： | 广东中山市埠湖医院,528451 |
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| 摘 要： | 目的：探讨齐拉西酮与奥氮平治疗精神分裂症的疗效及安全性。方法：共59例精神分裂症，分别以齐拉西酮（30例）及奥氮平（29例）治疗。采用阳性与阴性症状量表（PANSS）、治疗中出现的症状量表（TESS）评定疗效及不良反应。结果：齐拉西酮组有效率为80．0％，显效率为63．3％，与奥氮平组相当，对阴性症状疗效优于奥氮平组。结论：齐拉西酮治疗精神分裂症疗效较好，不良反应较少。
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| 关 键 词： | 齐拉西酮 奥氮平 精神分裂症 |
A comparative study between ziprasidone and olanzapine in the treatment of schizophrenia |
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| CHEN Yi-hua,ZHANG Wen-wei,HUANG Hai-feng,CHEN Bing-rong,CHEN Zhen-jie. A comparative study between ziprasidone and olanzapine in the treatment of schizophrenia[J]. Journal of Clinical Psychological Medicine, 2008, 18(4): 267-268 |
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| Authors: | CHEN Yi-hua ZHANG Wen-wei HUANG Hai-feng CHEN Bing-rong CHEN Zhen-jie |
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| Affiliation: | CHEN Yi- hua,ZHANG Wen-wei, HUANG Hai-feng, CHEN Bing-rong, CHEN Zhen-jie.( Buhu Hospital of Zhongshan, Zhongshan 528451, China) |
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| Abstract: | Objective:To investigate the clinical efficacy and side effects of ziprasidone and olanzapine for treating schizophrenia. Method:A total of 59 patients were divided into ziprasidone group(n=30)and olanzapine group(n=29).The clinical effects and side effects were evaluated with positive and negative symptom scales(PANSS) and treatment emergent symptom scales(TESS). Results:Curative effects of ziprasidone was similar to that of olanzapine.The effective rate and significant improved rate were 80.0% and 63.3%.But ziprasidone was better in treating negative symptom than olanzapine. Conclusion: Ziprasidone has good effects to treat schizophrenia and has less side effects. |
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| Keywords: | ziprasidone olanzapine schizophrenia |
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