109HH人工腱的超微结构研究

为探讨戊二醛合剂（ＭＧ）对人发的作用机理和筛选最佳浓度，对正常人发和经过４种不同浓度ＭＧ处理后的人发进行了超微结构研究。结果表明经４种不同药物浓度作用后的人发，表面和内部结构均有不同程度的改变，毛小皮翘起，鳞片间松驰、断裂，微丝软化和解聚并与基质融合。临床对人工腱的要求不仅在体内能够腱化，而且还要有一定强度，经比较４种浓度的ＭＧ中以５－１０％浓度为好，它使微丝解聚轻微，可保持较高强度，应当是首选浓度。

An ultrastructural study on 109HH artificial tendon

n order to determine the optimal concentration of mixt glutaraldehyde(MG)as a tenotosis promoterof human hair and to reveal its working mechanism,the ultrastructure of normal human hair and humanHair treated with four different concentrations of MG was studied.The results showed that the surface andinternal structure of the hair were changed in various degrees after the treatment with one of all four con-centrations of MG. The hair epidermicula was warped and became loose or broken among hair scales.Themicrofilaments in the hair was flxible,depolymerized and fused with the matrix. For satisfying clinical de-mand an ideal artificial tendon materials not only should be tenotosised in vivo,but also should have cer-tain intensity. Therefore,the present rusults suggested that 5-10%might be the optimal concentration ofMG,Depolymerisation of microfilaments was slight after the treatment with this concentration of MG sothat a higher intensity could remain.