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| 维生素D缺乏与心房颤动的研究现状 | |
| 引用本文： | 王凯歌,马茜钰,张锦. 维生素D缺乏与心房颤动的研究现状[J]. 中国临床药理学杂志, 2021, 0(2): 175-178 |
| 作者姓名： | 王凯歌 马茜钰 张锦 |
| 作者单位： | 兰州大学第一临床医学院;兰州大学第一医院心内科、甘肃省心血管疾病重点实验室 |
| 摘 要： | 维生素D是一种脂溶性维生素,作用于骨组织系统,维持人体的钙磷平衡,主要通过与靶器官上维生素D蛋白受体结合发挥生物学效应.近年来研究发现维生素D受体还存在于骨外组织,例如心肌细胞、内皮细胞、血管平滑肌细胞.维生素D缺乏与心房颤动的发生密切相关,涉及复杂的病理生理过程.本文就维生素D缺乏与心房颤动的研究进展进行综述. |
| 关 键 词： | 维生素D缺乏 心房颤动 肾素-血管紧张素-醛固酮系统 炎症 |
Research progress of vitamin D deficiency and atrial fibrillation |
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| WANG Kai-ge,MA Qian-yu,ZHANG Jin. Research progress of vitamin D deficiency and atrial fibrillation[J]. The Chinese Journal of Clinical Pharmacology, 2021, 0(2): 175-178 | |
| Authors: | WANG Kai-ge MA Qian-yu ZHANG Jin |
| Affiliation: | (The First Clinical Medical College,Lanzhou University,Lanzhou 730000,Gansu Province,China;Department of Cardiology,the First Hospital of Lanzhou University/Gansu Key Laboratory of Cardiovascular Diseases,Lanzhou 730000,Gansu Province,China) |
| Abstract: | Vitamin D is a fat-soluble vitamin,which acts on the bone tissue system to maintain the calcium and phosphorus balance in the human body.Recent studies have found that vitamin D receptors also exist in extracellular tissues,such as cardiomyocytes,endothelial cells,and vascular smooth muscle cells.Vitamin D deficiency is closely related to the occurrence of atrial fibrillation and involves complex pathophysiological processes.This paper reviews the research progress of vitamin D and atrial fibrillation. |
| Keywords: | vitamin D deficiency atrial fibrillation renin-angiotensin-aldosterone system inflammation |
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