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Micrometastatic bone marrow cells at diagnosis have no impact on survival of primary breast cancer patients with extensive axillary lymph node involvement treated with stem cell-supported high-dose chemotherapy
Authors:Schneeweiss, A.   Diel, I.   Hensel, M.   Kaul, S.   Sinn, H.-P.   Unnebrink, K.   Rudlowski, C.   Lauschner, I.   Schuetz, F.   Egerer, G.   Haas, R.   Ho, A. D.   Bastert, G.
Affiliation:1 University of Heidelberg, Department of Gynecology and Obstetrics, Heidelberg; 2 Institute for Gynecological Oncology, Mannheim; 3 University of Heidelberg, Department of Internal Medicine V, Heidelberg; 4 University of Heidelberg, Department of Pathology, Heidelberg; 5 University of Heidelberg, Coordination Center for Clinical Trials, Heidelberg; 6 University of Düsseldorf, Department of Hematology and Oncology, Düsseldorf, Germany
Abstract:
Backround: To determine the impact of micrometastatic bone marrowcells (MMC) on survival in high-risk primary breast cancer (HRPBC)patients treated with high-dose chemotherapy (HDCT) and autologousstem cell transplantation (ASCT). Patients and methods: Ninety-one HRPBC patients (73 patientswith
Keywords:high-dose chemotherapy   micrometastatic bone marrow cells   primary breast cancer   prognostic impact   survival
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