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| 我院160例酪氨酸激酶抑制剂致不良反应分析 | |
| 引用本文： | 叶晓兰,陈晶晶,张春红,石大伟,胡卢丰,张秀华. 我院160例酪氨酸激酶抑制剂致不良反应分析[J]. 中国药房, 2012, 0(42): 3997-3999 |
| 作者姓名： | 叶晓兰 陈晶晶 张春红 石大伟 胡卢丰 张秀华 |
| 作者单位： | 温州医学院附属第一医院药剂科,浙江温州325000 |
| 摘 要： | 目的：观察酪氨酸激酶抑制剂治疗癌症的不良反应。方法：定期随访服用酪氨酸激酶抑制剂的160例患者，对其服药后的情况进行分析、总结。结果：酪氨酸酶抑制剂引起的不良反应以皮肤系统损害最为常见（占43．88％），其次是消化系统和呼吸系统。结论：临床上要对使用酪氨酸酶抑制剂的患者加强监测，以免严重不良反应的发生。 |
| 关 键 词： | 表皮生长因子受体 酪氨酸激酶抑制剂 药品不良反应 |
Analysis of 160 Cases of Adverse Drug Reaction of Tyrosine Kinase Inhibitor in Our Hospital |
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| YE Xiao-lan,CHEN Jing-jing,ZHANG Chun-hong,SHI Da-wei,HU Lu-feng,ZHANG Xiu-hua. Analysis of 160 Cases of Adverse Drug Reaction of Tyrosine Kinase Inhibitor in Our Hospital[J]. China Pharmacy, 2012, 0(42): 3997-3999 | |
| Authors: | YE Xiao-lan CHEN Jing-jing ZHANG Chun-hong SHI Da-wei HU Lu-feng ZHANG Xiu-hua |
| Affiliation: | (Dept. of Pharma- cy, The First Affiliated Hospital of Wenzhou Medical College, Zhejiang Wenzhou 325000, China) |
| Abstract: | OBJECTIVE： To observe adverse drug reactions （ADR） of tyrosine kinase inhibitors in the treatment of cancer. METHODS： 160 patients who took tyrosine kinase inhibitors were followed up regularly, and their conditions were summarized and analyzed after medication. RESULTS： The most common ADR caused by tyrosine kinase inhibitor was lesion of skin damage （43.88%）, followed by digestive system and respiratory system. CONCLUSION： We should strengthen monitoring for patients who use tyrosine kinase inhibitors, so as to avoid the occurrence of serious ADR. |
| Keywords: | Epidermal growth factor receptor Tyrosine kinase inhibitor Adverse drug reaction |
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