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Two cases of cytomegalovirus infection revealed by hearing loss in HIV-infected patients
Authors:J.L. Meynard  M El Amrani  M.C. Meyohas  I Fligny  J Gozlan  W Rozenbaum  E Roullet  J Frottier
Affiliation:1Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France;2Service de Neurologie, Hôpital Saint-Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France;3Service d'Oto-Rhino-Laryngologie. Hôpital Saint-Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France;4Service de Bactériologie-Virologie. Hôpital Saint-Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France;5Service des Maladies Infectieuses et Tropicales, Hôpital Rothschild, Paris, France
Abstract:
Neurological complications are particularly common during HIV infection. Among various opportunistic diseases, cytomegalovirus (CMV) is one of the most frequent causes of central and peripheral neurological manifestations. Previously, there have been several reports of cranial nerve infection by CMV, but to our knowledge, no cases of auditory nerve involvement have been described. We report two cases in which CMV infection was revealed by involvement of the VIIIth cranial nerves. Cytomegalovirus (CMV) infection is frequent in severely immunodeficient patients infected by human immunodeficiency virus (HIV). The main targets of CMV are the retina, gastrointestinal tract and central nervous system. We describe two cases in which neurologic CMV infection was revealed by hearing loss.
Keywords:Author Keywords: AIDS   hearing loss   cytomegalovirus
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