乳腺癌的中医证型及用药规律研究

目的:探讨乳腺癌的中医证型分布及用药规律。方法:检索2000—2015年中国期刊全文数据库、维普数据库、万方数据库关于中医药治疗乳腺癌的相关文献,提取纳入文献的中医证候及用药信息,进行统一规范化处理后,建立乳腺癌中医治疗数据库,对其临床证候类型及用药情况进行相关频次分析。结果:纳入的45篇中医药治疗乳腺癌的文献中,中医证型主要为肝郁型、痰瘀毒热型、气血两虚型、冲任失调型、气阴两虚型,所占比例依次为48.4%、18.8%、15.6%、14.1%、3.1%;中药治疗乳腺癌的高频药物中归肝经的药物频率达33.3%。结论:在中医药辅助治疗乳腺癌的过程中从肝论治占主导地位。

Study on TCM Syndrome and Medication Rule of Breast Cancer

Objective: To explore TCM syndrome and medication rule of breast cancer. Methods: Relevant documents of TCM in treating breast cancer in CNKI, CQVIP and W anFang Data were retrieved from the year of 2000 to 2015. TCM syndromes and medication information in documents were extracted. Database of TCM in treat-ing breast cancer were built after united and standardized management. Relevant frequency of clinical TCM syn-drome and medication condition was analyzed. Results:All 45 documents of TCM in treating breast cancer were in-corporated at last, TCM syndromes can be divided into liver-stagnation type, phlegm-stasis type, Qi and blood defi-ciency type, incoordination between the Chong and Ren meridians type, Qi and Yin deficiency type, the rates were 48.4%, 18.8%, 15.6%, 14.1% and 3.1% in turn. The frequent rate of high-frequency medicines belonged to liver meridian in Chinese herbs for breast cancer reached to 33.3%. Conclusion:Treatment starting from liver occupies dominant status in the process of TCM in treating breast cancer.