非骨水泥型假体周围早期骨密度变化临床观察

为观察非骨水泥型假体置换术后周围骨密度的变化,对25例非骨水泥型人工假体置换患者分别于术后1周、3个月及6个月应用双能X线骨密度仪,按Grune1]分7个测量兴趣区测量假体周围骨密度.结果显示假体周围骨密度术后3个月平均丢失11.7%,6个月平均丢失17.77%.其中以1和7区明显,1区术后3、6个月分别减少21.25%、25.55%(P＜0.01),7区术手3、6个月分别减少22.80%、32.14%(P＜0.01).说明假体置换术后早期周围骨密度均有不同程度的减少,其中以假体近端(1、7区)明显,且骨量丢失以术后前3个月最为显著.

CLINICAL OBSERVATIONS ON EARLY CHANGES IN CEMENTLESS-PERIPROSTHETIC BONE MINERAL DENSITY

In order to observe the early changes in periprosthetic bone mineral density(BMD) after cementless prosthetic hip replacement,cementless prosthetic hip replacements were made on 25 patients according with the selective standards,the periprosthetic BMD in 7 regions of interest(ROI) based on the Crune's classification were measured by dual energy X-ray absorptiometry one week,three months and six months post-operatively,respectively.The results showed that the periprosthetic BMD losses in 3 and 6 months post-operatively averaged 11.7 % and 17.77 %,respectively,especially in Region 1 and Region 7: Region 1 had 21.25 % and 25.55 % decreases in post-operative 3 and 6 months,respectively;and Region 7 had 22.80 % and 32.14 % decreases in the same time,respectively,showing varied-degree decreases in periprosthetic BMD after prosthesis hip replacement,especially in the proximal prosthesis(Region 1 and Region 7),and significant bone loss in the first three months post-operatively.