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Gene expression in brain: a window on ethanol dependence,neuroadaptation, and preference
Authors:Hoffman Paula L  Miles Michael  Edenberg Howard J  Sommer Wolfgang  Tabakoff Boris  Wehner Jeanne M  Lewohl Joanne
Affiliation:Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA. paula.haffman@uchsc.edu
Abstract:
This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.
Keywords:DNA Microarrays    Gene Expression    Selected Lines    Transgenics    Null Mutants    Alcohol Preference    Alcohol Tolerance    Alcoholism
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