| 血清和胸腔积液CEA、NSE、CYFRA21-1、SCC-Ag联检对肺癌诊断的临床意义 |
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| 引用本文： | 卞宝祥,胡楠,吴风雷,杨成喜. 血清和胸腔积液CEA、NSE、CYFRA21-1、SCC-Ag联检对肺癌诊断的临床意义[J]. 放射免疫学杂志, 2008, 21(5): 391-394 |
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| 作者姓名： | 卞宝祥 胡楠 吴风雷 杨成喜 |
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| 作者单位： | 江苏省连云港市第一人民医院肿瘤科,222002 |
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| 摘 要： | 目的：探讨血清和胸腔积液中肿瘤标志物CEA、NSE、CYFRA21-1、SCC-Ag联检对肺癌诊断的临床意义。方法：采用放射免疫分析检测54例肺癌患者及35例肺良性病变（BLD）患者血清和胸腔积液中CEA、NSE、CYFRA21-1、SCC-Ag的水平。结果：肺癌组血清和胸腔积液中CEA、NSE、CYFRA21-1、SCC-Ag水平均明显高于肺良性病变组（P〈0.01）。胸腔积液中CEA、NSE、CYFRA21-1、SCC-Ag含量明显高于血清含量（P〈0.01）,血清和胸腔积液CEA、NSE、CYFRA21-1、SCC-Ag联检阳性率分别可达83.33%和92.59%。结论：血清和胸腔积液中CEA、NSE、CYFRA21-1、SCC-Ag联检可提高肺癌诊断的阳性率,在肺癌诊断中有重要价值。
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| 关 键 词： | 癌胚抗原 神经元特异性烯醇化酶 细胞角蛋白19片段21-1 鳞状细胞癌相关抗原 肺癌 |
Clinical Diagnostic Significance of Combined Detection of Serum and Pleural Effusion Levels of CEA, NSE, CYFRA21-1, SCC-Ag in Patients with Lung Cancer |
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| Affiliation: | Bian Baoxiang,Hu Nan,Wu Fenglei,et al. (Department of Oncology,Lianyungang Municipal 1st People＇s Hospital,Lianyungang,Jiangsu 222002) |
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| Abstract: | Objective To appraise the clinical diagnostic significance of combined detection of serum and chest fluid levels of CEA, NSE, CYFRA21-1 and SCC-Ag in patients with lung cancer. Methods Serum and pleural effusion contents of CEA, NSE, CYFRA21-1 and ACC-Ag were determined with RIA in 54 patients with lung cancer and 35 patients with benign lung disorders. Results The serum and pleural effusion contents of CEA, NSE, CYFRA21-1 and SCC-Ag patients with lung cancer were significantly higher than those, in patient... |
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| Keywords: | CEA NSE CYFRA21-1 SCC-Ag lung cancer |
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