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肝病患者血清总胆汁酸测定的临床意义
引用本文:陈秀琴,刘树业,高秀登.肝病患者血清总胆汁酸测定的临床意义[J].天津医药,2002,30(7):413-414.
作者姓名:陈秀琴  刘树业  高秀登
作者单位:300170,天津市第三中心医院检验科
摘    要:目的:观察各种肝病患者血清总胆汁酸(TBA)水平变化,探讨其在肝病发展过程中的作用。方法:采用循环酶速率法,检测各种肝病患者TBA水平。结果:急性期各种肝病患者,血清总胆汁酸含量明显升高,与对照组比较有显著性差异(P<0.01),在恢复期,各种肝病患者总胆汁酸较活动期下降,与对照组比较,除急肝和慢肝轻度患者无统计学意义外,其余各种肝病患者血清TBA仍有显著性差异。结论:血清总胆汁酸(TBA)在肝病病情进展中起重要作用,其水平与肝损害程度密切相关。

关 键 词:肝病  血清  总胆汁酸  测定  临床意义  肝炎  肝硬化

Clinical Significance of Level of Serum Total Bile Acids in Patients with Liver Disease
CHEN Xiuqin.LIU Shuye.GAO Xiudeng.Clinical Significance of Level of Serum Total Bile Acids in Patients with Liver Disease[J].Tianjin Medical Journal,2002,30(7):413-414.
Authors:CHEN XiuqinLIU ShuyeGAO Xiudeng
Institution:CHEN Xiuqin.LIU Shuye.GAO Xiudeng Department of Clinical Laboratory,Tianjin Third Central Hospital,China 300170
Abstract:Objective: To explore the clinical significance of the level of serum total bile acids (TBA) in patients with liver disease. Methods: The level of serum TBA in 205 patients with liver disease was determined with kinetic method. Results: The level of serum TBA in patients with acute liver disease was obviously higher than that in healthy control group(P < 0.01). The level of serum TBA in active stage of liver disease was higher than that in recovery stage. Conclusion: TBA is very important in the pathogenesis of liver disease and its level is closely related with the degree of liver damage.
Keywords:bile acids and salts  liver diseases  hepatitis  liver cirrhosis
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