原发性肝癌术后肝功能变化临床分析

目的探讨原发性肝癌病人手术前后肝功能变化规律。方法回顾性分析1990—2005年收治的142倒原发性肝癌，按术前肝功能Child分级分为2组。ChildA级102例（A组），ChildB级40例（B组）。分析比较两组病人手术前、后的主要肝功能指标变化。结果原发性肝癌病人丙氨酸转氨酶（ALT）、天冬氨酸转氨酶（AST）和血清胆红素于手术后均升高，术后3d迭较高水平，后呈现逐渐下降的趋势。A、B两组在升高幅度及下降趋势上差异有显著性，肝功能ChildA级病人2周后上述指标恢复到术前水平。结论原发性肝癌病人手术前、后的主要肝功能指标变化与术前肝功能Child分级密切相关。

The clinical analysis of hepatic function change after primary hepatic carcinoma operation

Objective To investigate the change of hepatic function in the patients with primary hepatic carcinoma after operation.Methods Hepatic function of 142 patients with primary hepatic carcinoma admitted between 1990 and 2005 was analyzed retrospectively.The patients were divided into two groups:102 patients with Child A in group A and 40 with Child B in group B.The change of hepatic function in two groups after operation was compared.Results The alanine aminotransferase (ALT),aspartate aminotransferase (AST), and serum bilirubin (SB) were found increasing 3 days after operation and then decreasing.The amplitude of increasing and the tendency of decreasing were significantly different between two groups.The hepatic function turned to normal in the group with child A grade.Conclusion Before and after operation,the Child degree is direct correlative with the change of mainly hepatic function.