良性前列腺增生伴慢性炎症的组织学特征和临床参数研究

目的探讨良性前列腺增生伴随慢性炎症的组织学特征以及临床参数，为治疗提供有效的方案。方法收集病理诊断符合良性前列腺增生的60例前列腺标本，观察前列腺组织中炎症细胞的浸润情况及组织学特征。将60例患者分为良性前列腺增生合并慢性前列腺以及单纯良性前列腺增生患者等两组，对两组患者的前列腺体积、发病的年龄等进行比较分析。结果60例患者前列腺标本均可发现炎症细胞浸润。对患者组织进行镜下观察，可发现有52例前列腺周边型炎症浸润，占患者总数86．7％；腺型则有38例患者，占总数63．3％；间质型患者则有34例，占总数56．7％。同时拥有三种类型的有30例，占患者总数50．0％。单纯性的良性前列腺增生患者组与良性前列腺增生合并慢性前列腺炎症组患者相比较而言，在平均发病年龄之上有着显著性差异（P〈0．05），并且在前列腺平均体积方面也有着显著性差异（P〈0．05）。结论良性前列腺增生合并慢性前列腺炎症的患者前列腺体积比单纯良性前列腺增生患者增加较显著，同时炎症浸润在良性前列腺增生的发生和病情发展当中起到了很大的作用，在临床诊断和治疗的过程之中需要对这一点重视。

RESEARCH OF THE HISTOLOGIC CHARACTERISTICS AND CLINICAL PARAMETERS IN HUMAN BENIGN PROSTATIC HYPERPLASIA WITH CHRONIC INFLAMMATION

Objective To investigate the histological characteristics and clinical parameters of the benign prostatic hyperplasia with chronic inflammation, providing solutions for treatment. Methods In 60 cases of pathological diagnosed prostatic specimens of benign prostatic hyperplasia, characteristics and infiltration of inflammatory cells were observed in prostate tissue. These 60 patients were divided into benign prostatic hyperplasia with chronic prosta- titis group and only benign prostatic hyperplasia group, the prostate volume, incidence with age of the two groups were analyzed and compared. Results In all the 60 patients＇prostate specimens can be found the infiltration of inflammato- ry cells, Microscopic observation of the tissue of the patients, found prostatic peripheral inflammation infiltration in 52 cases, account for 86. 7% in total; Adenal type 38 cases, accounting for 63.3 % of the total; interstitial patients was 34 cases, accounting for 56.7% of the total number. At the same time have three types in 30 cases, 50.0% in total. Groups of patients with only benign prostatic hyperplasia and benign prostatic hyperplasia complicated with chronic prostatitis patients in comparison, there are significant differences in the average age of onset （p 〈 0. 05 ）, and theaverage volume of prostate also had significant difference （p 〈 0. 05 ）. Conclusion Compared with the only benign prostatic hyperplasia patients, the prostate volume of benign prostatic hyperplasia with chronic prostatitis increased significantly, At the same time, inflammatory infiltration in the occurrence and severity of benign prostatic hyperplasia stage plays a great role, so in the clinical diagnosis and treatment, this point should be pay attention to.