外周动静脉同步换血治疗新生儿高胆红素血症24例疗效分析

目的:探讨输液泵全自动控制经外周动静脉同步换血治疗重度新生儿高胆红素血症的疗效及其对血液中其他成分的影响。方法:选取我院符合换血指征的重度高胆红素血症患儿24例,均采用输液泵全自动控制外周动静脉同步换血治疗,换血前后均行血常规、血生化、血气分析、肝肾功能及血糖等检查。结果:24患儿例换血前平均血清总胆红素水平为(469.74±45.36)μmol/L,换血后为(245.60±15.31)μmol/L,换出率为52.28%,平均换血量150¹80 mL/kg,换血前后总胆红素水平比较差异具有统计学意义(P<0.05)。结论:输液泵全自动控制外周动静脉同步换血治疗新生儿高胆红素血症疗效肯定,具有简单、实用及安全等优点,值得临床进一步推广。

An Analysis of Efficacy on Peripheral Arteriovenous Synchronous Exchange Transfusion for the Treatment of 24 Cases of Neonatal Hyperbilirubinemia

Objective： To discuss the efficacy of automated synchronous exchange transfusion for the newborn with severe neonatal hyperbilirubinemia by infusion pumps and its influence on other blood components. Methods： 24 Cases of severe neonatal hyperbilirubinemia with indications for blood transfusion in our hospital were chosen, and were treated with automated synchronous exchange transfusion by infusion pumps. Before and after exchange transfusion, blood routine, blood biochemistry, blood gas analysis, function of liver and kidney and blood sugar were detected. Results： Atter exchange transfusion, an average total bilirubin level of 24 cases decreased from （469.74± 45.36） μmol/L to （245.60± 15.31） μ mol/L, the exchange rate and the average of blood exchange were 52.28% and 150-180 mL/kg respectively. There was significant difference before and after exchange transfusion （P 〈0.05）. Conclusion： The clinical efficacy of anutomated synchronous exchange transfusion by infusion pumps for treating the newborn with hyperbilirubinemia was proved affirmative, and this method is simple, safe and effective, worthy of generalization at clinical.